Should" is right up there with "we" as a dangerous word, one of the signposts you'll see as you're sliding down the slope to signing away your life and rights to collectivism. For example, the sentence "Should we want to
Some Ohio lawmakers believe they have the ultimate resolution to the battle between the Ohio Tobacco Prevention Foundation and the state: eliminate the foundation and give its money to a state agency.
The National Institutes of Health will award $3 million in grants to up to six recipients for research into medications that can be used to treat marijuana-related disorders.
A Michigan man temporarily lost custody of his son after mistakenly buying the 7-year-old an alcoholic Mike's Hard Lemonade at a Detroit Tigers game last month.
The nonprofit Center for Science in the Public Interest urged several Miller Brewing Co., Foster's, and Diageo to stop allowing logos for their beers to be used on tee shirts sold at Forever 21, a retailer popular with teenage girls.
A new study shows that therapists can effectively use virtual-reality (VR) technology to stimulate alcohol craving in order to train patients in coping and resistance skills.
Doctors can double the likelihood of patients quitting smoking by briefly discussing their tobacco use and encouraging them to quit, according to British researchers.
Background:The objectives of this study were to determine rates of prenatal care utilization in Winnipeg, Manitoba, Canada from 1991 to 2000; to compare two indices of prenatal care utilization in identifying the proportion of the population receiving inadequate prenatal care;
Background:Conserved Wnt ligands are critical for signalling during development; however, various factors modulate their activity. Among these factors are the Secreted Frizzled-Related Proteins (SFRP). We previously isolated the SFRP-4 gene from an involuting rat mammary gland and later showed that
Background:Allosteric coupling, which can be defined as propagation of a perturbation at one region of the protein molecule (such as ligand binding) to distant sites in the same molecule, constitutes the most general mechanism of regulation of protein function. However,
Background:Breast cancer (BC) mortality is declining such that the number of survivors of BC in the community is increasing. BC survivors report a range of sequelae from their cancer and its management beyond the period of their immediate treatment. Previous
Background:TRP channels have been shown to be involved in tumour generation and malignant growth. However, the expression of these channels in breast cancer remains unclear. Here we studied the expression and function of endogenous TRPC6 channels in a breast cancer
Background:We introduce a QTL-mapping algorithm based on Statistical Machine Learning (SML) that is conceptually quite different to existing methods as there is a strong focus on generalisation ability. Our approach combines ridge regression, recursive feature elimination, and estimation of generalisation
Background:Alveolar macrophages (AM) avidly bind and ingest unopsonized inhaled particles and bacteria through class A scavenger receptors (SRAs) MARCO and SR-AI/II. Studies to characterize the function of these SRAs have used AMs from MARCO or SR-AI/II null mice, but this
Background:Currently, there is a gap between purely theoretical studies of the topology of large bioregulatory networks and the practical traditions and interests of experimentalists. While the theoretical approaches emphasize the global characterization of regulatory systems, the practical approaches focus on
AimsImplantable defibrillators are considered life-saving therapy in heart failure (CHF) patients. Surprisingly, the recent Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) reached an opposing conclusion from that of numerous other trials about their survival benefit in patients with advanced
